Statins

Statin drugs - British Heart Foundation

Statins are drugs which lower the level of cholesterol in your blood. There are different types of statins, but they all work in the same way.

Why do I need to lower my cholesterol?

Statins reduce the amount of ‘bad cholesterol’ your body makes. Cholesterol is essential for your body to work well, but too much ‘bad cholesterol’ (called low-density lipoprotein or LDL) is unhealthy.

High levels of ‘bad cholesterol’ in your blood can lead to fatty deposits building up in your arteries. This can increase your risk of developing cardiovascular disease which includes conditions such as coronary heart disease (angina and heart attack) and stroke.

Your body will always make cholesterol, so if you stop taking a statin, it’s likely your cholesterol levels will rise. If you are prescribed a statin, you need to take it every day. Statins are most beneficial when you take them on a long-term basis.

Who needs to take statins? 

Some GPs prescribe statins to people who are healthy, but at high risk of developing cardiovascular disease. Statins can help lower their risk.

You can ask your GP for a health check to find out if you are at risk of cardiovascular disease.

Your GP or cardiologist can also prescribe statins to prevent you having further problems if you have already had a heart attack, a stroke or peripheral artery disease, or if you have diabetes.

When should I take my statin?

It’s important to take your medication regularly as prescribed. The statins that doctors prescribe most often should be taken at night. Check with your doctor or pharmacist when you should be taking your statin.

Most statins come as tablets. The most common one is simvastatin.

Look up your medication on the Medicine Guides website.

Do I need to avoid other drugs or any foods?

Check with your doctor or pharmacist before you take any other drugs. Taking certain drugs together may affect how well they work.

If you’re taking simvastatin, avoid grapefruit and grapefruit juice as they can increase your risk of side effects.

Do statins have side effects?

Like all medication, statins have potential side effects that are usually mild, easy to recognise, reversible and very rarely dangerous. Statins are among the safest and the most studied drugs available today. You should tell your GP if your symptoms are getting worse or if you develop any new symptoms.

Statins target the liver cells where cholesterol is made. Before you start taking statins, you will have a blood test to check how well your liver works. You will have a follow-up blood test a few months later. If your liver is affected, your doctor may want to reduce your dose or change your statin to another kind of medication that lowers your cholesterol.

Find out about other possible side effects from our Statins information sheet.

Can I buy statins over the counter?

Low-dose statins are available at pharmacies without a prescription, but they are not a substitute for prescription statins or for making lifestyle changes to reduce your cholesterol level. If you are at high risk of heart disease, your doctor may prescribe a statin for you.

What's the difference between the types of statins?

All types of statins do the same job. Lots of people don’t need a strong statin to reduce their cholesterol level. Your GP or cardiologist will find the right statin for you, depending on your medical history and the cholesterol level they think you should aim for.

If you’re sensitive to one statin, you might not be sensitive to another. You should have a blood test after any change of statin to see how effectively the new drug is lowering your cholesterol.

Statins and pregnancy

If you’re pregnant, breastfeeding or planning a pregnancy, you shouldn’t take statins. If you’re already taking statins but would like to become pregnant, speak to your GP first.

How else can I lower my cholesterol?

You can also lower your cholesterol by: